Where can i buy amfexa. Just to add my two penn’orth, I was a little surprised to come across this thread; I’ve been more satisfied with Amfexa (for ADHD) than with the generic formulation and am / have been minded to ask them to prescribe that.  But, I base that on a different criterion, not necessarily incompatible with some of the findings here; I wonder if anyone else has found likewise. With Amfexa, I get a much faster onset of symptom relief (~5 min. fasted, 20 min. with food) than I do with the generics from Auden McKenzie (20-30 min. fasted, 30-60 min. with food). I experienced this as a substantial advantage, in terms of ADHD relief, because I could use it in reaction to a phone call or on arrival at a meeting and the results would be near instantaneous.

Where can i buy amfexa. By chance, or by a GP whose attitude was “my ignorance is better than your knowledge” and insisted on prescribing by the 28 days, I got switched back unexpectedly to the Auden McKenzie version (which is what I’d started out on, finding it effective enough then) and I was not happy at all; they might as well have been sugar pills, at least until some long while post ingestion. They certainly weren’t; on one occasion I managed to take a double dose by honest accident, believing I hadn’t already taken a dose for the apparent lack of activity at 20-30min. (I don’t recommend it, for the record.)

This made sense based on the ingredients; crospovidone is a dispersant, helping the tablet to break apart. It would seem to have more business being in my dexamfetamine tablet than paraffin, starch, talc, stearic acid, acacia et al. So, on the face of it, I much preferred Amfexa. I still do, I think.

Where can i buy amfexa. But, this thread is thought-provoking. I had been prescribed 15mg qds, with agreement from the prescriber that I could use 20mg tds if preferred, the bottom line being the same. Unsurprisingly, 20mg was preferred more often than not. But so was four doses a day, so I took a tolerance break (2 or 3 weeks, not much fun) until 15mg doses worked… sort of… for about a week… and back to 20mg. This is all with Amfexa. To an extent, I’ve not been exactly surprised by an inclination to re-dose at shorter intervals (we all know what stimulants are…) and didn’t give much consideration to the brand and formulation in this respect. The idea of reverting to something so subjectively inferior that I can end up double-dosing by accident is quite unappealing. 

Where can i buy amfexa. All the same, when I first took dexamfetamine (5mg, Auden McKenzie) and scrutinised it in full-blown “trip report” mode (at this point I may as well mention Asperger’s, sensory sensitivity, and GAD), the time to baseline was 7 hours, of which (up to) the first four hours was clinically relevant. Thinking about it, I reckon I re-dosed at about 4h intervals with the generic dexamfetamine, whereas with Amfexa that’s more like 3 hours to maintain optimum symptom coverage, and at ~5h it’s dead in the water. I’ve fairly much learned to work around that by accepting that symptom control through my typical ~18h day isn’t going to happen, and effectively using it pro re nata when something warrants it, and putting up with it otherwise. This is not an entirely happy compromise; I have been minded to push for 20mg qds and would have an honest (and observable) case for it, too, but I still don’t imagine that it will be very popular. 

Where can i buy amfexa. So, this all gets more interesting/complicated/FUBAR. I suspect that the same daily dose of the Teva/Auden McKenzie product would produce a lesser effect size, more slowly and for longer, which, at first glance, appears relative to my needs as a lose/lose scenario; I would anticipate greater persistence of appetite suppression through meal times, and greater risk for insomnia absent an offensively regimented dosing schedule (which would go out the window in no time; the subjective cost of living by alarms for this and bells for that is not one that I would welcome). I can quite imagine, for those treating narcolepsy, that what to me is an annoyance would be a disaster. Any comments / thoughts invited.

Alcohol

Where can i buy amfexa. To the last poster, regarding the concern about alcohol… the SPC for Amfexa says “Alcohol may exacerbate the CNS adverse reactions of psychoactive medicinal products, including dexamfetamine. It is therefore advisable for patients to abstain from alcohol during treatment.”, but this is not quite the screaming warning that you cite. The bold, screaming warning (at least now my local pharmacy no longer prints it in bold block capitals) that reads “May cause drowsiness. If affected do not operate machinery or drive. Avoid alcoholic drink.”, this last worded as a direct imperative, is plastered indiscriminately on almost all psychotropic medications in the UK by executive order, a consequence of the drug driving legislation. 

Where can i buy amfexa. Whilst in principle I support that legislation, dumb warnings of this latter sort are a disservice to patients and an unnecessary barrier either to ADHD treatment, or to the moderate enjoyment of alcohol where appropriate. I was first mortified, then infuriated to discover this warning; I had read the (generic) PIL in its entirety, which made no mention of avoiding alcohol, and my psychiatrist and I had discussed my (fairly modest) consumption of alcohol with no concern on his part; my pharmacist had made the proper enquiries about any potential interactions and likewise had no advice to offer about avoiding alcohol. So, a couple of weeks in, I had half a bottle of Rioja with my dinner; only then did my eyes alight on the screaming bold “AVOID ALCOHOLIC DRINK.”. Momentarily, I really felt quite upset; I had been scrupulously careful to do everything by the book, and now I had screwed up. How could an intelligent person blithely ignore the pharmacy label? 

Where can i buy amfexa. Déjà vu, as it turned out. The identical wording was to be found on a box of quetiapine (probably the most sedating of the atypical anti-psychotics) and a quick phone call to a friend confirmed that it could also be found on zopiclone (hypnotic) and mirtazapine (anti-depressant). I was furious. My pharmacist is an intelligent, erudite professional and I should be able to put faith in his instructions without these being confounded by some Home Office functionary. I voiced my indignance to my psychiatrist, who affirmed that half a bottle of Rioja with my paella seemed reasonable enough to him, and to an accompanying psychologist, who mused that there could be people taking that instruction literally and avoiding moderate social drinking because of their ADHD medication where it might be no bad thing. 

Where can i buy amfexa. With all the usual disclaimers (I am not a doctor; this is not medical advice and does not substitute for it, your mileage may vary, past performance is not necessarily a guide to the future, you may not get back the full capital invested and in this case, you probably wouldn’t want to…) I looked into it a little further. I don’t positively advise drinking, but, a quick search of PubMed turned up a few late 1970s articles suggesting species-dependent prolongation of d-amp metabolism in rodents. Precious few studies could I find in humans, but (hot off the press), readers may be interested in the findings of Newcorn et al., “A Randomized Phase I Study to Assess the Effect of Alcohol on the Pharmacokinetics of an Extended-release Orally Disintegrating Tablet Formulation of Amphetamine in Healthy Adults.” which didn’t find a lot of difference in the pharmacokinetics. 

Those planning to enjoy a drink after all should, of course, be mindful of the advice of drug harm reduction forums, one of which reminds us that

“Drinking on stimulants is risky because the sedative effects of the alcohol are reduced, and these are what the body uses to gauge drunkenness. This typically leads to excessive drinking with greatly reduced inhibitions, high risk of liver damage and increased dehydration. They will also allow you to drink past a point where you might normally pass out, increasing the risk. If you do decide to do this then you should set a limit of how much you will drink each hour and stick to it, bearing in mind that you will feel the alcohol and the stimulant less. Extended release formulations may severely impede sleep, further worsening the hangover.” (source: drugs.tripsit.me/amphetamine)

Where can i buy amfexa. but this cautions against indiscriminate use (a caution valid of alcohol and amphetamines jointly and severally) not towards puritanical abstinence. The language of the SPC is reasonable enough; the SPC for Amfexa is more complete and generally less scare-mongery than the generic SPC because it sources data from, and satisfies the requirements of, several different European countries. Just to further confound the issue, I note with dismay that the MHRA has approved as ‘bioequivalent’ a substantively inferior generic formulation.  I’m aware that the specifications allow pharmacokinetic parameters within 80% to 125% of the reference product, and doubt that many could discern the variance in a 5% lower C_max (dietary variance could achieve that), but, a product that provides an AUC_0-t of just 89.25% of the reference product will be noticeably unacceptable to anyone who has need of it in the first place. I think it may be a good idea to make a point of asking for consistency and asking that it be written into shared care protocols, otherwise there will be a lot more victims of such pharmaceutical fraud.